It was his first victory ever against a player ranked in the top two and it avenged the semi-final loss at the Rio Olympics where Murray went on to win gold and Nishikori settled for bronze.
Former world number one Maria Sharapova eased past defending champion Peng Shuai 6-3, 6-1 at the Tianjin Open on Saturday to reach her first WTA final in almost two and a half years.
Former world number one Rafael Nadal displayed more signs of a return to top form with a ruthless 6-2, 6-1 hammering of Stanislas Wawrinka to reach the semi-finals of the Shanghai Masters on Friday.
Rafael Nadal was made to wait before his second-round Rogers Cup match due to several rain delays but did his part to put the schedule back on track with a speedy 6-2 6-3 win over Frenchman Benoit Paire on Wednesday.
Newly-crowned Korea Open champion P V Sindhu dished out another splendid performance edging past Japan's Minatsu Mitani for the second time in as many weeks to reach the second round of the women's singles at the Japan Open Super Series, in Tokyo, on Wednesday.
IMAGES from matches on Day 9 at the French Open at Roland Garros
With the physical demands of modern-day tennis taking its toll the tournament will start without four of the top 11 in the ATP rankings including defending champion Stan Wawrinka who ended his season early with a knee injury.
P V Sindhu opens her campaign in the China Open women's singles against Evgeniya Kosetskaya of Russia, in Fuzhou, China, on Tuesday.
IMAGES from Day 5 of the 2020 US Open in New York on Friday.
The defence ministry has lost sight of what it intended to achieve -- which was to nurture private defence firms that would compete on equal terms with the 9 defence PSUs and the 41 Ordnance Factory Board factories.
World No 2 Rafael Nadal brushed aside American Jared Donaldson 6-1, 6-1 and will next face Diego Schwartzman after the Argentine beat Roberto Carballes 6-3, 6-1.
World number five Roger Federer delivered a tennis masterclass to beat rising star Alexander Zverev 6-1, 6-3 and clinch a record ninth Halle Open title on Sunday as he lay down a marker in the lead-up to Wimbledon.
Roger Federer faced down local battler John Millman 4-6, 7-6(2), 6-4, 4-6, 7-6(8) in a five-set thriller on Friday night to reach the last 16 of the Australian Open. Defending champion Novak Djokovic thumped Japanese Yoshihito Nishioka 6-3, 6-2, 6-2 in the third round of the Australian Open on Friday to stay on course for a record-extending eighth title at Melbourne Park. Images from Day 5 of the 2020 Australian Open.
Rafael Nadal left German qualifier Yannick Maden no hope as he booked his ticket for the third round of the French Open in ruthless fashion with a 6-1, 6-2, 6-4 victory.
Fifth seed Maria Sharapova averted an early exit on a sweltering day in Flushing Meadows. Updates from Wednesday's play.
Serena Williams must navigate a heavily American quarter of the draw including sister Venus to complete a calendar sweep of the four Grand Slams, while two sensational quarter-finals loom on the men's side after Thursday's U.S. Open draw.
Reigning champions Novak Djokovic and Serena Williams have been named top seeds for the Australian Open starting on Monday.
Cilic's booming serve lacked its usual accuracy and Germany's Kohlschreiber was able to control long rallies, pushing the towering Croatian around the court with pinpoint groundstrokes en route to a quick victory.
India's singles challenge came to a tame end after Yuki Bhambri lost 3-6, 3-6 to fifth seeded Canadian Vasek Pospisil, in the quarter-final of the ATP Chennai Open on Friday.
Mumbai is observing the sixth anniversary of the dastardly attacks that shook the city
Stan Wawrinka outslugged Japanese sixth seed Kei Nishikori 4-6, 7-5, 6-4, 6-2 in energy-sapping humidity at Flushing Meadows on Friday to set up a US Open final against world number one Novak Djokovic.
Top seeds Novak Djokovic and Serena Williams face challenging early tests at the US Open following Friday's draws for the year's last Grand Slam starting on Monday.
Novak Djokovic and Serena Williams are top seeds at the major starting Monday
Roger Federer became the latest big name to get sucked up by a whirlwind called Nick Kyrgios as the Australian tyro sent the Swiss top seed spinning out of the Madrid Masters in the second round on Wednesday.
Novak Djokovic sauntered past Spaniard Feliciano Lopez to reach the quarter-finals of the Shanghai Masters on Thursday but Andy Murray had to claw past big-serving American John Isner after losing a first-set tiebreaker.
Novak Djokovic extended his winning streak at the China Open to 27 matches with a 6-2, 6-2 demolition over big-serving American John Isner on Friday.
Saina Nehwal is better equipped to win a medal in Rio in August than the Indian shuttler was when she claimed a bronze at the London Olympics four years ago, former All England champion Prakash Padukone said.
Here are some of the most stunning moments of the week that was.
A summary of sports events and sports persons, who made news on Wednesday.
Olympic bronze-medallist Saina Nehwal stood just one win away from clinching her maiden China Open title after she stormed into the finals of the USD 700,000 Super Series Premier tournament in Fuzhou.
Ukrainian second seed Elina Svitolina ended Naomi Osaka's remarkable recent run with a 6-4, 6-2 triumph over the Indian Wells champion in the second round of the Miami Open on Friday.
The 36-year-old Australian Open champion arrived in the Dutch port city at the weekend knowing a run to the semi-finals will move him ahead of Rafael Nadal in the ATP standings.
It was double delight for India as crowd favourites Saina Nehwal and Kidambi Srikanth clinched their maiden women and men's singles titles at the India Open Super Series badminton tournament in New Delhi.
There comes a moment in all great sporting careers when the puzzle fits together and for Kei Nishikori it arrived on a sweltering early September afternoon in New York.
Two-time champion Novak Djokovic thumped Spain's David Ferrer 6-4, 6-2 to march into the last four of the Shanghai Masters on Friday and set up a semi-final showdown with third seed Roger Federer.
Big-serving Canadian Milos Raonic made a strong return to competition on Friday by beating Viktor Troicki 6-3, 7-5 to reach the third round of the Miami Open.
Germany defender Nico Schulz scored a late winner as their new-look side snatched a 3-2 win away to the Netherlands in their opening Euro 2020 Group C qualifier on Sunday, an absorbing clash that swung in fortunes from one side to the other.
Third seed Stan Wawrinka was sent packing in the round of 16 at the BNP Paribas Open in California on Wednesday and was very nearly joined by Rafael Nadal, who pulled off a Houdini-like escape to reach the last eight.
Summary of sports events and persons who made news on Saturday
Second seed Angelique Kerber stayed on track in her quest to unseat Serena Williams as world number one by beating Mirjana Lucic-Baroni of Croatia 6-2, 7-6(7) on Wednesday to reach the third round of the US Open.